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Clinical data
Pronunciation/ s ɪ l ˈ d ɛ n ə f ɪ l / sil- DEN -ə-fil
Trade namesViagra, Revatio, others
AHFS/Drugs.comMonograph
MedlinePlusa699015
License dataEU  EMA:  by INN, US   FDA: Sildenafil
Pregnancy categoryAU: B1 US: B (No risk in non-human studies)
Routes of administrationBy mouth (tablets), IV
ATC codeG04BE03 ( WHO )
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Pharmacokinetic data
Bioavailability41% (mean) [1]
Protein binding~96%
MetabolismLiver: CYP3A4 (major route), CYP2C9 (minor route)
MetabolitesN -desmethylsildenafil (~50% potency for PDE 5 )
Elimination half-life3–4 hours
ExcretionFeces (~80%), urine (~13%) [2]

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Although you are probably happy to visit your doctor to discuss most health issues, when it comes to erectile dysfunction you may not feel comfortable having a face-to-face consultation. viagra talk to frank. Any websites claiming to sell viagra should be avoided as they will not be regulated by the Royal Pharmaceutical Society of Great Britain RPS and there may be concerns over quality, safety and effectiveness of the products they provide. Viagra, like all drugs, has potential side effects so patients may need follow-up assessments after they begin taking the drug.


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