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Paroxetine
Clinical data
Trade namesPaxil, Pexeva, Seroxat, others
AHFS/Drugs.comMonograph
MedlinePlusa698032
License dataUS   FDA: Paroxetine
Pregnancy categoryAU: D US: D (Evidence of risk)
Routes of administrationOral
ATC codeN06AB05 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityExtensively absorbed from the GI tract, but extensive first-pass metabolism in the liver [1] [2] [3] [4]
Protein binding93–95% [1] [2] [3]
MetabolismExtensive, hepatic (mostly CYP2D6-mediated) [1] [2] [3]
Elimination half-life21 hours [1] [2] [3]
ExcretionRenal (64%; 2% unchanged and 62% as metabolites), Faecal (36%; <1% unchanged) [1] [2] [3]

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Increased incidence of adverse effects, including serotonin syndrome.

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Paxil (Generic)

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Paroxetine, 3 reviews:

Comment №1 about product

This condition can be life-threatening and may include:


5 / 5 stars
Comment №2 about product

When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount. Seizures or convulsions or . Call your healthcare provider right away or go to the nearest emergency room if you have any of the following symptoms, especially if they are new, worse, or worry you:


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Comment №3 about product

Serotonin antagonist may partially reverse antidepressant and other effects. Additive serotonergic effects. Paroxetine is an antidepressant that comes in 10, 20, 30, 40mg pills and can be sold only with a prescription.


2 / 5 stars
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