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Azathioprine: MedlinePlus Drug Information

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Azathioprine
Clinical data
Pronunciation/ ˌ æ z ə ˈ θ aɪ ə ˌ p r iː n / [1]
Trade namesAzasan, Imuran and others
AHFS/Drugs.comMonograph
MedlinePlusa682167
License dataUS   FDA: azathioprine
Pregnancy categoryAU: D US: D (Evidence of risk)
Routes of administrationMainly by mouth (sometimes initially intravenous)
ATC codeL04AX01 ( WHO )
Legal status
Legal statusAU: S4 (Prescription only) CA : ℞-only UK: POM (Prescription only) US: ℞-only
Pharmacokinetic data
Bioavailability60±31%
Protein binding20–30%
MetabolismActivated non-enzymatically, deactivated mainly by xanthine oxidase
Elimination half-life26–80 minutes (azathioprine) 3–5 hours (drug plus metabolites)
ExcretionKidney, 98% as metabolites

Use of azathioprine and the risk of cancer in inflammatory bowel disease

Your doctor will order tests before, during, and after your treatment to see if your blood cells are affected by this medication. However, the researchers noted that the risks do not necessarily warrant the withdrawal of azathioprine.

A drug used to treat inflammatory bowel disease, arthritis and vasculitis as well as to prevent organ rejection in transplant patients has been identified as an important contributor to skin cancer development.

Store at room temperature away from moisture, heat, and light.

Wear protective clothing and use sunscreen SPF 30 or higher when you are outdoors. Your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely using azathioprine.

Your pharmacist can provide more information about azathioprine. Tell your doctor if any of these symptoms are severe or do not go away: It could harm the unborn baby. The researchers conducted a mutational signature analysis of cSCC tumors from 37 patients, many of whom had been on azathioprine.

Azathioprine has not been approved by the Food and Drug Administration FDA for the treatment of Crohn's disease or ulcerative colitis, but doctors may sometimes prescribe azathioprine to treat these conditions. Top of Page This information does not replace the advice of a doctor.

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Some people using azathioprine have developed a rare fast-growing type of lymphoma cancer. What side effects can this medication cause? If you have had a kidney transplant, there may be a higher risk that you will develop cancer even if you do not take azathioprine.

It is usually taken once or twice a day after meals ― terbinafine tablets ip 250 mg. This list is not complete. HSTCL is a very serious type of cancer that often causes death within a short period of time.

Accessed September 10, It is also used to treat symptoms of rheumatoid arthritis. Azathioprine is used to treat inflammatory bowel disease, arthritis, and vasculitis, as well as to prevent organ rejection in transplant patients.

Tell your doctor at once if you develop signs of infection. Continue to take azathioprine even if you feel well.

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Educational Resources

If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at Your doctor may order a test to see if you have this risk factor before or during your treatment ‒ allergic reaction to phenazopyridine.

Skip the missed dose if it is almost time for your next scheduled dose. This has occurred mainly in teenagers and young imuran and cancer using azathioprine or similar medicines to treat Crohn's disease or ulcerative colitis. Instead, the best way to dispose of your medication is through a diflucan candida die off take-back program.

Your doctor may perform blood tests to make sure you do not have conditions that would prevent you from safely using azathioprine.

The immune system helps your body fight infections. What should I know about storage and disposal of this medication?

Azathioprine may harm the fetus — . Talk to your doctor about your individual risk.

Imuran and cancer
Do not stop taking azathioprine without talking to your doctor Follow your doctor's dosing instructions very carefully Other drugs may interact with azathioprine The researchers conducted a mutational signature analysis of cSCC tumors from 37 patients Follow the directions on your prescription label carefully
Azathioprine can pass into breast milk and may harm a nursing baby This medication can affect fertility your ability to have childrenwhether you are a man or a woman For medical advice relating to your personal condition Nature Communications Take the missed dose as soon as you remember it
Azathioprine has not been approved by the Food and Drug Administration FDA for the treatment of Crohn's disease or ulcerative colitis It was already known that use of azathioprine leads to increased photosensitivity to UVA light Azathioprine is in a class of medications called immunosuppressants Content may be edited for style and length Take azathioprine exactly as directed
You may not be able to continue taking other arthritis medications together with azathioprine Azathioprine may cause side effects What happens if I overdose?Do not take more or less of it or take it more often than prescribed by your doctor Azathioprine lowers your body's immune system

PRO: Monotherapy Using 6-MP or Azathioprine for IBD is Dead

What should I know about storage and disposal of this medication? Learn how we develop our content.

Azathioprine is used to prevent your body from rejecting a transplanted kidney with buy imuran online. If you need surgery, tell the surgeon ahead of time that you are using azathioprine.

If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Where can I get more information? Azathioprine lowers your body's immune system. Keep the bottle tightly closed when not in use.

Alexandrov, Karin J. Tell your doctor if you have or have ever had cancer and if you are taking or have ever taken alkylating agents such as chlorambucil Leukerancyclophosphamide Cytoxanor melphalan Alkeran for cancer. Take the missed dose as soon as you remember. What should I avoid while taking azathioprine?

What special precautions should I follow?Azathioprine is used to treat inflammatory bowel disease
Where can I get more information?Do not stop taking azathioprine without talking to your doctor

They found a new mutational signature, signature 32, which correlated with time on azathioprine ritalin and sertraline, according to the study.

Healthwise, Incorporated, disclaims any warranty or liability for your use of this information. Call your doctor if you have any unusual problems while you are taking azathioprine. Continue to take azathioprine even if you feel well.

Tell your doctor if l artane of these symptoms are severe or do not go away: Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides.

Content may be edited for style and length. It may take up to 12 weeks before you feel the full benefit of azathioprine. Not all possible interactions are listed in this medication guide. Your doctor may order a test to see if you have this risk factor imuran and cancer or during your treatment.

Your doctor will order tests before, during, and after your treatment to see if your imuran and cancer cells are affected by this medication. Azathioprine is used with other medications to prevent transplant rejection attack of the transplanted organ by the immune system in people who received kidney transplants.

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Imuran and cancer

Use effective birth control, and tell your doctor if you become pregnant during treatment. If you experience any of the following symptoms, imuran and cancer your doctor immediately: Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

What special precautions should I follow?

Store it at room temperature and away from excess heat and moisture not in the bathroom. Talk to your doctor about your individual risk. Although most of the immunosuppressed patients who received azathioprine were also taking at least 1 other immunosuppressive drug, 3 of the tumors with signature 32 were from patients who had received azathioprine alone.

Take azathioprine exactly as directed. If you develop any of these symptoms during your treatment, call your doctor immediately:

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. These symptoms may start gradually and get worse quickly.

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Imuran, 2 reviews:

Comment №1 about product

Instead, the best way to dispose of your medication is through a medicine take-back program. Some teenage and young adult males who took azathioprine alone or with another medication called a tumor necrosis factor TNF blocker to treat Crohn's disease a condition in which the body attacks the lining of the digestive tract causing pain, diarrhea, weight loss, and fever or ulcerative colitis a condition which causes swelling and sores in the lining of the colon [large intestine] and rectum developed hepatosplenic T-cell lymphoma HSTCL. Your use of this information means that you agree to the Terms of Use.


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Comment №2 about product

It was already known that use of azathioprine leads to increased photosensitivity to UVA light, probably contributing to development of skin cancers. However, the researchers noted that the study provides evidence for an association between the novel mutational signature and long-term azathioprine use. Azathioprine can increase your risk of developing skin cancer.


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